Association of Raised C-Reactive Proteins With Prolonged ICU Stay in Children with Bronchopneumonia: A Cross Sectional Study

Authors

  • Shazia Rizwan Assistant Professor, Paediatrics Department, Ghurki Trust Teaching Hospital affiliated with LMDC,Lahore,Pakistan.
  • Sara Hassan Senior Registrar, Paediatrics Department, Ghurki Trust Teaching Hospital affiliated with LMDC,Lahore,Pakistan.
  • Madiha Iqbal Senior Registrar, Paediatrics Department, Ghurki Trust Teaching Hospital affiliated with LMDC,Lahore,Pakistan.
  • Sobia Shahalam Assistant Professor, Paediatrics Department, Ghurki Trust Teaching Hospital affiliated with LMDC,Lahore,Pakistan.
  • Tayyaba Noor Professor, Paediatrics Department, Ghurki Trust Teaching Hospital affiliated with LMDC,Lahore,Pakistan.
  • Rizwan Waseem Professor, Paediatrics Department, Ghurki Trust Teaching Hospital affiliated with LMDC,Lahore,Pakistan.

DOI:

https://doi.org/10.51846/jucmd.v4i1.3176

Keywords:

Bronchopneumonia, C-Reactive Proteins, Paediatric Intensive Care Unit, World Health Organization

Abstract

Objective 

To study the association of raised CRP with prolonged ICU stay in children with bronchopneumonia at Ghurki Trust Teaching Hospital, Lahore, Pakistan.

Methodology

This cross-sectional study was conducted in Paediatric Intensive Care Unit of Ghurki Trust Teaching Hospital, Lahore, Pakistan, for a duration of six months (June 2023 to December 2023). Out of 127 children admitted into ICU, 82 met the inclusion criteria, aged 2-60 months, diagnosed with bronchopneumonia. Upon admission, blood sample was taken for CRP levels and these levels were correlated with ICU stay, TLC count, O2 dependency, and antibiotics duration of the patients. Patients were divided into five groups based on CRP counts. CRP counts less than 0.3 mg/dL were taken as normal. CRP counts from 0.4-0.9 mg/dL were taken as mild, 1-10 mg/dL were considered moderate, 11-49 mg/dL were considered marked, and ≥50 mg/dL were considered severe.

Results

Out of 82 patients, 45 (54.88%) were males and 37 (45.12%) were females. This study found that raised CRP was present in 73 (89.02%) out of 82 children (p<0.04). Amongst 73 (89.02%), 08 (10.96%) patients had mild elevation of CRP, 36 (49.32%) had moderate elevation, 22 (30.14%) had marked, 07 (9.59%) had severe elevation. Moreover, a direct relation was observed among CRP and ICU stay (3.82±3.12), O2 requirements (3.72±3.07), TLC (13.36±5.18), antibiotic treatment duration (9.52±3.94) of broncho pneumonic patients.

Conclusion

Higher CRP levels significantly result in longer ICU stays and higher oxygen requirements in children with bronchopneumonia.

 

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Published

28-08-2024

How to Cite

1.
Shazia Rizwan, Hassan S, Madiha Iqbal, Sobia Shahalam, Tayyaba Noor, Rizwan Waseem. Association of Raised C-Reactive Proteins With Prolonged ICU Stay in Children with Bronchopneumonia: A Cross Sectional Study. J Univ Coll Med Dent. [Internet]. 2024 Aug. 28 [cited 2025 Jul. 5];4(1):44-9. Available from: https://journals.uol.edu.pk/jucmd/article/view/3176

Issue

Volume 4 Issue 1

Section

Original Articles

License

Copyright (c) 2024 Dr. Shazia Rizwan, Dr. Sara Hassan, Dr. Madiha Iqbal, Dr. Sobia Shahalam, Dr. Tayyaba Noor, Dr. Rizwan Waseem

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