Radical Scavenging and Antibacterial Potential of Green Fabricated Silver Nanoparticles Using Benincasa fistulosa Leaves Extract

Radical Scavenging and Antibacterial Potential of Green Silver Nanoparticles

Abstract

Green synthesis of nanoparticles, especially by plant sources, has significant attention for their abundant bioactive metabolites and eco-friendly nature. This study aims to developed sustainable method for nanoparticles synthesis and exploring their radical scavenging and antibacterial potential. This study focuses on the green synthesis of silver nanoparticles using Benincasa fistulosa leaves extract, which acts as a plant-derived stabilizing agent for silver nitrate solution. The synthesized nanoparticles were characterized using different techniques such as scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), UV-Vis spectroscopy, and X-ray diffraction (XRD). Radical scavenging potential was assessed using 2, 2-Diphenyl-1-picrylhydrazyl (DPPH), total phenolic contents (TPC) and total flavonoid contents (TFC). The highest antibacterial activity was shown against Bacillus subtilis 56±2.86, and antioxidant activities were evaluated using disk diffusion and minimum inhibitory concentration (MIC) methods. The results demonstrate that the silver nanoparticles exhibited good antimicrobial and antioxidant properties, highlighting their potential for various biomedical applications.